My Doc advised me Cymbalta 30mg, Paxil (paroxetine) CR 25mg, Zyprexa 5mg, tizanidine 4mg for severe anxiety, panic, depression. I feel no improvement. Advice please?

See ans. Reassess meds with prescribing doctor who knows you best. See your primary care doctor for any possible medical factors that might contribute to anxiety or depression symptoms: check thyroid, vit D, iron, etc. Consider psychotherapy for coping strategies and support. I hope this helps.