14 doctors weighed in:
How effective is metformin for ovulation in pcos women that are not diabetic or overweight?
14 doctors weighed in

Dr. Vered Lewy-Weiss
Pediatrics - Endocrinology
7 doctors agree
In brief: Should help
Metformin is often first line treatment for pcos, even in women who are not overweight and don't have diabetes.
Insulin resistance is usually still a component of pcos which contributes to the menstrual and hormonal irregularities. Metformin increases Insulin sensitivity which is the reason it is such a good medication for pcos.

In brief: Should help
Metformin is often first line treatment for pcos, even in women who are not overweight and don't have diabetes.
Insulin resistance is usually still a component of pcos which contributes to the menstrual and hormonal irregularities. Metformin increases Insulin sensitivity which is the reason it is such a good medication for pcos.
Dr. Vered Lewy-Weiss
Dr. Vered Lewy-Weiss
Thank
1 comment
Dr. Vered Lewy-Weiss
I just learned that clomiphene citrate is the number 1 choice to induce ovulation in women with PCOS who are trying to conceive. Inducing ovulation in women who are not trying to conceive may still be achieved with metformin.
Dr. Michael Traub
Fertility Medicine
3 doctors agree
In brief: Not Very
For most women, metformin is no longer considered the first treatment used in pcos women.
Actually, there are concerns that it ls less effective than other therapies and may actually increase risk of miscarriage when used alone for ovulation induction. In appropriate pcos patients, it can be useful for other reasons. At this point, most studies shows Clomiphene is the preferred therapy.

In brief: Not Very
For most women, metformin is no longer considered the first treatment used in pcos women.
Actually, there are concerns that it ls less effective than other therapies and may actually increase risk of miscarriage when used alone for ovulation induction. In appropriate pcos patients, it can be useful for other reasons. At this point, most studies shows Clomiphene is the preferred therapy.
Dr. Michael Traub
Dr. Michael Traub
Thank
1 comment
Dr. Vered Lewy-Weiss
I wasn't aware of the consensus statement about using clomiphene citrate in favor of metformin to increase fertility. Thanks for that update. This same consensus statement supports using metformin in women with PCOS and glucose intolerance trying to conceive. I believe that metformin remains a mainstay of treatment for females who have PCOS and do not want to conceive. Please share thoughts.
Dr. Mark Perloe
Fertility Medicine
2 doctors agree
In brief: Metformin
The study suggesting metformin is not of value did not use the generic which is more effective.
It did not advise combining metformin with diet and exercise. The majority of women i see have not been advised about diet and usually are taking far too little mediation.

In brief: Metformin
The study suggesting metformin is not of value did not use the generic which is more effective.
It did not advise combining metformin with diet and exercise. The majority of women i see have not been advised about diet and usually are taking far too little mediation.
Dr. Mark Perloe
Dr. Mark Perloe
Thank
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