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What can cause huge itchy hives that last for 2 days? Responds to antihistamine but returns hours later. No known allergies but strong family history.

1 doctor weighed in
Dr. Justin Greiwe
Internal Medicine - Allergy & Immunology

In brief: Acute Urticaria/Hive

Acute urticaria (hives) is common, affecting 20% of the population.
Acute hives resolve within 6 weeks (most patients fit into this category). Hives can become chronic if last more than 6 weeks. Common viral/bacterial infections can trigger an outbreak, however medications, foods, and stings can also cause acute hives but have the potential to lead to more serious complications. See Allergist

In brief: Acute Urticaria/Hive

Acute urticaria (hives) is common, affecting 20% of the population.
Acute hives resolve within 6 weeks (most patients fit into this category). Hives can become chronic if last more than 6 weeks. Common viral/bacterial infections can trigger an outbreak, however medications, foods, and stings can also cause acute hives but have the potential to lead to more serious complications. See Allergist
Dr. Justin Greiwe
Dr. Justin Greiwe
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