2 doctors weighed in:

Is there an antihistamine you could recommend that would have a very low probability of crossing the blood brain barrier to deter mental impairment?

2 doctors weighed in
Dr. Al Hegab
Internal Medicine - Allergy & Immunology
1 doctor agrees

In brief: 2nd generation

antihistamines as desloratadine or fexofenadine have much lower probability of crossing to the brain, in recommended daily doses, some people would still be sedated despite the recommended dose, yet to try different formulations to reach the desired effect, safety critical jobs as pilots need to work with their doctors closely, you better see an allergist/immunologist for alternatives, take care

In brief: 2nd generation

antihistamines as desloratadine or fexofenadine have much lower probability of crossing to the brain, in recommended daily doses, some people would still be sedated despite the recommended dose, yet to try different formulations to reach the desired effect, safety critical jobs as pilots need to work with their doctors closely, you better see an allergist/immunologist for alternatives, take care
Dr. Al Hegab
Dr. Al Hegab
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