Yes can u get pregnant after 1 depo provera (medroxyprogesterone) shot?

Most likely not. Not if the injection was given as directed by the manufacurer. Given the 1st inj only during the first 5 days of a normal menstrual period, only w/in the first 5 days postpartum if not breastfeeding, or only at the 6th postpartum week if exclusively nursing.