premenstrual dysphoric disorder, bi-polar. Periods bad. Tried all meds. Can't metabolize. Wants 2 try Nova Ring. It helped her friend. What your views?

More information. "Tried all meds" is unlikely to be true. More likely it's "fed up with trying meds," perhpas with reason. But which meds, at what doses, for what length of time? and what is meant by "can't metabolize"? This would be important information.