ALT reading -50 ALP reading -140 Bilirubin 74 Is this suggestive of liver failing Metastic colon cancer?

Liver function. The enzymes (ALP & ALT) are indicative of only mild liver dysfunction. The rising bili suggests that some degree of bile obstruction may be occurring. This could be due to the mechanical obstruction of small ducts by metastatic disease. But the liver has a large degree of reserve capacity, so full liver failure is unlikely to be final cause of death even with very bulky mets.
Liver. No I do not think it is the liver failing. I think it is. sign of liver involvement in the metastaticc process.

Related Questions

Metastic colon cancer with liver mets. Bilirubin was 12, then went to 95 and now 85. Is it starting to drop again?

Very high . The difference between a bilirubin of 95 and 85 is not clinically meaningful. Be sure to follow up with your oncologist however, as the situation is complex. Hope this helps! Read more...
Bilirubin levels. Well it seems to be trending down. Lab results in general can be variable....sometimes a little higher sometimes a little lower. A difference of 10 points would definitely be considered a real drop. Hang in there! Read more...
No. An elelvated bilirubin in metastatic colon cancer to liver is not good prognaostically A level of 95 dropping slightly to 85 would suggest that an obstructive process was causing the elevation. Whether chemo was employed would be questionable since a high bilirubin wound exclude use of chemo. Scans should reveal obstruction in main bile duct and allow a stent to control bile level. Read more...

Can high increasing bilirubin in metastic colon cancer with liver mets cause death? What is prognosis? Other LFT "s are normal

Bilirubin. the high bilirubin will not cause death in this situation, it likely is a sign that the bile ducts are blocked up by metastatic cancer in the liver. . Read more...
Comfort measures. The jaundice won't cause death itself, but will make for discomfort like itchiness. Death in advanced cancer usually comes from infection or vital structure failure. So do your best to treat any infections and treat any symptoms of pain or itchiness. Best to make sure that relationships are in best shape with loved ones. That's the best comfort. Read more...

Metastic colon cancer. Ct scan showed disease stable after 3 chemo rounds. Largest liver met 8 cm. Bilirubin was 12, 19, 12, 33, 51, now 74. What can this be?

It is not unusual.. ...for biochemical markers, such as bilirubin measured in the blood, to not seem consistent with what appears anatomically..images on a CT scan. In all likelihood it means that the metastatic colon cancer is functionally advancing, destroying liver cells. However, there would be a small chance that the bilirubin is elevated for some other cause.Your doctor will help you sort this out. All the best. Read more...
Hyperbili. If jaundiced, intrahepatic (liver caused) levels of bilirubin are likely here. One cause is hepatitis, possibly from chemo, or from the met. In some cases, high bilirubin in adults may be caused by blockages in the bile ducts, depending on where the met is. Symptoms include digestive distress and pain in the abdomen, hard to distinguish from chemo caused side effects. Talk to your cancer doctor. Read more...

ALP level has gone from. 74 to 175, this mean chemo not working in a metastic colon cancer pt?

Not always reliable. I assume that from ALP you meant Alkaline Phosphatase(a type of liver function test). But avoid using abbreviations. This test can sometimes be correct in showing tumor progression but we need more information than this test alone in order to assess tumor response. The additional tests that help are measuring the liver size , checking CEA level(Blood test) and for making final decision, CT scan. Read more...