Constant feeling of having to urinate. Going pee makes the feeling worse. UTI, diabetes, STD's, Cancer etc has been ruled out. Any thoughts?

OAB vs Interstitial. Perhaps you have interstitial cystitis? Check out Once we know it's none of the above after a thorough evaluation, then we can chalk it up to an overactive bladder (OAB) and discuss various antimuscarinics & beta 3 agonist. Check out &
PROSTATITIS EVAL. R/O prostatitis v Epididymitis tough to treat. Hopefully you have seen a urologist recently. Tx with doxycycline. I would recheck labs /UA C&S. & testosterone if no response ,cipro (ciprofloxacin) may be needed for 8-10wks. Recheck labs and culture. You also need abdominal/pelvic/prostate US R/O prostate stones. Also switch to gluten free diet Cipro (ciprofloxacin) may also be tried if no change.