Which medication controls or cures fifficult hypertension with the least amount of dangerous side effects to liver, kidneys, muscles...all body parts?

Depends. There is no single medication that does everything. All BP meds lower BP about 10 points or so with individual differences. The best one for you depends on what other health issues you may have: kidney disease? Angina? Congestive heart failure? Diabetes? Prostate enlargement? There are different best BP meds for each.