Yes. It is common to use colace (docusate sodium) or docusate long term, especially when taking narcotics.
Yes. Stool softeners are safe to use regularly. However, I suggest that people add a fiber supplement and increase water intake first. Laxatives are another thing entirely, and should not be used regularly without a doctor's direction. This can lead to dependence of the colon on the laxative, which is not reversible.