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What effect does the LDL receptor have in cholesterol diseases?

1 doctor weighed in
Dr. William Cromwell
Clinical Lipidology

In brief: Clears LDL Particles

Ldl is low density lipoprotein, a particle that carries cholesterol in the blood.
If LDL particles are increased (high LDL particle number) more particles enter the artery wall and increase cardiovascular disease (cvd) risk. Ldl receptors (ldlr) bind and remove LDL particles from the blood. Low ldlr increases cvd risk. Statin drugs increase ldlr causing lower LDL levels and decreased cvd risk.

In brief: Clears LDL Particles

Ldl is low density lipoprotein, a particle that carries cholesterol in the blood.
If LDL particles are increased (high LDL particle number) more particles enter the artery wall and increase cardiovascular disease (cvd) risk. Ldl receptors (ldlr) bind and remove LDL particles from the blood. Low ldlr increases cvd risk. Statin drugs increase ldlr causing lower LDL levels and decreased cvd risk.
Dr. William Cromwell
Dr. William Cromwell
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