Bloodwork: AST43. Other liver values high normal but double a year ago. Cholesterol very high:total 255, LDL 178. Always low before. Liver disease?

Maybe fatty liver ? Fatty liver is incredibly common predominantly due to: high alcohol intake, diabetes, high cholesterol, obesity. The more of these risks you have the greater the chance of fatty liver. Addressing these risks is an important step to correcting fatty liver. Distinguish hepatosteatosis (fatty liver) from steatohepatitis (fatty liver with abnormal liver tests) versus MANY other possibilities--see doc.