Who should not use Irinotecan injections?

Irinotecan. "Irinotecan hydrochloride injection is contraindicated in patients with a known hypersensitivity to the drug or its excipients." See: http://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2361c88c-124e-4f6c-aef2-c70612f0eb64.