How effective is the FOLFIRI chemotherapy regimen for treating colon cancer?

Some effect. Single drug chemotherapy has failed to produce significant improvement in colorectal Ca. Combination chemo as in FOLFIRI with irinotecan has added about 5 month prolongation in survival and with immunotherapy using Avastin (bevacizumab) or Erbitux an additional 2-3 months can be observed. Chemo-Immuno with a mAb targeting the immunogenic protein appears to be giving further enhancement.

Related Questions

How effective is the FOLFIRI-Bevacizumab chemotherapy regimen for treating colon cancer?

Moderately useful. FOLFIRI-Bev is the standard, commonly used first line chemotherapy for metastatic Colon cancer. It can add about 12 to 18 months extra to your life such that an average patient can live for 2 to 3 years(some live upto 5-6 years... depending on sites of metastases and their response to chemotherapy. You need tell us more about your history such as dates of diagnosis and treatments/results so far?? Read more...

How effective is the IFL chemotherapy regimen for treating colon cancer?

It is an old regimen. It is one of the effective treatment regimens for metastatic colon Cancer which first appeared on the scene more than 5 years back and became popular for a while to be soon upgraded with other more effective modern regimens which also include Avastin (bevacizumab) in combination with chemotherapy. Read more...

How effective is the XELOX chemotherapy regimen for treating colon cancer?

Relatively good. According to the Journal of Clinical Oncology XELOX is a highly effective first-line treatment for metastatic colon cancer. To be more accurate (55%) of patients achieve a response, and 30% experience disease stabilization for more than 3 months following treatment. Always consult with your oncologist. Read more...

How effective is the IFL-Bevacizumab chemotherapy regimen for treating colon cancer?

Better than chemo. Combining bevacizumab (BV)—a recombinant, humanized mAb targeting VEGF with irinotecan, fluorouracil (FU), and leucovorin (LV; IFL) has increased survival of patients with metastatic colorectal Ca compared with IFL It appears necessary to use combination therapy in treatment and has supported the concept that the use of immunochemotherapy improves results over chemo alone. Read more...

Is folfiri alone effective for metastic colon cancer than irinotecan alone?

Two drugs vs one dru. Folfiri contains two drugs in the combination: 5-FY(Folinic acid) and Irinotecan. This combination is more effective than using irinotecan alone. It is often combined with Avastin (bevacizumab) in case it is being used to treat colon cancer. Read more...

What can my mother expect who has colon cancer and will be on the folfox 4 regimen for chemotherapy?

It depends. Results depend upon the stage of cancer. It is active for the adjuvant treatment and in metastatic disease. The side effects can include nausea and diarrhea. Occasionally there can be some blood count issues. The other side effect can be cold related temporary nerve injury that lasts a very short time. There also is a more long term nerve injury. Most people do tolerate this well. Hope this helps. Read more...

What is the most effective chemotherapy for stage 3 colon cancer?

Standard of care. Standard of care -adjuvant chemotherapy for stage 3 colon cancer will be a combination of 5-fluorouracil and oxaliplatin or oral Capecitabine and oxaliplatin. Read more...
See an oncologist . Colon chance chemotherapy has a lot options now, and a thoughtful short and potential long term plan is what i necessary. Some oncologist believe that one day soon metastatic colon cancer may even be able to be treated as a chronic disease. I have certainly seen patients live for a decade with stage 4 disease. I wish you all the best. Read more...

How effective r chemotherapy uft pills in metastic colon cancer?

Some response. meds like Xeloda have some tempoary benefit suppressing DNA function as an oral 5FU (fluorouracil). Long term responses are not seen requiring combination therapy to give an optimjum response. Eventually if cancer does show a good response, malignant stem cells will repopulate the site of the original metastasis. Read more...

Ihow effective are uft chemotherapy pills for metastic colon cancer?

Modestly effective. Fluoropyrimidines (5-FU, Capecitabine and UFT) as a class have modest activity and one of these 3 needs to be combined with Oxaliplatin and or Irinotecan to achieve best results ,as combination chemo is far superior in efficacy than any single chemo drug. Read more...