4 doctors weighed in:

Why is Effexor officially indicated for anxiety, but Pristiq (desvenlafaxine) only used off label for it? Seems strange given their relation.

4 doctors weighed in
Dr. Maria Guerra
Pharmacology
2 doctors agree

In brief: Pristiq (desvenlafaxine) is newer

Effexor and Pristiq (desvenlafaxine) do work in the same way, Pristiq (desvenlafaxine) is simply the active metabolite of Effexor. The answer is that Effexor has been out much longer than Pristiq (desvenlafaxine).
Drug companies must demonstrate effectiveness for different indications through expensive clinical trials to get FDA approval for that condition. If Pristiq (desvenlafaxine) is proven to be effective for anxiety, FDA will approve it for that indication.

In brief: Pristiq (desvenlafaxine) is newer

Effexor and Pristiq (desvenlafaxine) do work in the same way, Pristiq (desvenlafaxine) is simply the active metabolite of Effexor. The answer is that Effexor has been out much longer than Pristiq (desvenlafaxine).
Drug companies must demonstrate effectiveness for different indications through expensive clinical trials to get FDA approval for that condition. If Pristiq (desvenlafaxine) is proven to be effective for anxiety, FDA will approve it for that indication.
Dr. Maria Guerra
Dr. Maria Guerra
Thank
Dr. Heidi Fowler
Psychiatry
1 doctor agrees

In brief: Agree w Dr Guerra

In order to have an FDA indication , the drug must have been specifically tested for that condition.
Pristiq is newer to the market.

In brief: Agree w Dr Guerra

In order to have an FDA indication , the drug must have been specifically tested for that condition.
Pristiq is newer to the market.
Dr. Heidi Fowler
Dr. Heidi Fowler
Thank
Get help from a real doctor now
Dr. Eric Weisman
Board Certified, Neurology
33 years in practice
9M people helped
Continue
111,000 doctors available
Read more answers from doctors