I have irregular period for the pass 4yrs now. I have a 10 year old daughter. When my daughter was four year I have one miscarriage since then no preg?

Irregular periods. That many years without a pregnancy mean you may have a hormonal problem. A very common problem can be polycystic ovarian syndrome (or PCOS). Recommend that you see a gynecologist or endocrinologist who can evaluate you for PCOS and other hormonal problems (thyroid disease, elevated prolactin). Any hormonal problem can prevent pregnancy and increase your risk for miscarriage if you get pregnant.