Can seroquel (quetiapine) cause you to feel nothing when ejaculating? This has never happened to me before and I started the medicine recently.

Talk to your doctor. It is possible to have sexual dysfunction associated with many psychiatric medications. These side effects include erectile dysfunction, delayed orgasm and loss of orgasm. Years ago a particular antipsychotic was known for retrograde ejaculation. It was thought it may be a form of birth control. In your case, talk to your doctor about your medication. You have several options. This is reversible.