Best way to get pregnant? Best friend has been trying for a very long time with no luck. She wants kids badly, do you have any advice that might help?

Hard to say. Most list the average duration of "trying " before success is 6 months in normal couples. They would only suggest a workup for fertility concerns after a year of effort. Sometimes a visit to the OB can help eliminate some obvious issues, while both prospective parents would be studied for a fertility work up.