Terrible heartburn and acid reflux while taking a 3-wk course of daily diflucan. Typical side effect? Ok to take Zantac (ranitidine) or a PPI?

Gastric upset with abdominal pain are well known side-effects of this drug, but what you are describing is quite severe and you should consult with your doctor. It is OK to take ranitidine (Zantac) or a PPI, but you should really be seen and evaluated if this is not relieved or continues after discontinuing the medication. Would you like to video or text chat with me?

"The stomach-related side effects that you usually see are 7% of patients experienced some nausea and 2% vomiting while on diflucan.

Heartburn or acid reflux are not commonly known ones. There are no drug-related interactions between Zantac (ranitidine) and Diflucan, but Diflucan can increase PPI drug levels. Use of the two together is better under the supervision of a prescribing doctor." Would you like to video or text chat with me?