2 doctors weighed in:

In metastic colon cancer do the size and number of metastases matter ?

2 doctors weighed in
Dr. Myron Arlen
Surgery - Oncology
1 doctor agrees

In brief: Yes

In colon cancer as with most malignancies as the lesion increases in size the greater the population of mutated cells with varying surface glycoproteins defining different sites of metastasis.
With the metastasis alreadyu present each of these cells express a mutated form of mitochondrial DNA acting as immunogenic inhibitory molecules making treatment more difficult.

In brief: Yes

In colon cancer as with most malignancies as the lesion increases in size the greater the population of mutated cells with varying surface glycoproteins defining different sites of metastasis.
With the metastasis alreadyu present each of these cells express a mutated form of mitochondrial DNA acting as immunogenic inhibitory molecules making treatment more difficult.
Dr. Myron Arlen
Dr. Myron Arlen
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