3 doctors weighed in:

What can cause a false positive for dysplastic nevi on pathology?

3 doctors weighed in
Dr. Marilda Chung
Pathology
1 doctor agrees

In brief: Can be difficult

Identifying dysplastic nevi can be difficult.
There is a spectrum of changes in nevi, benign ->mild/moderate dysplasia->severe dysplasia->in-situ melanoma ->malignant (melanoma). There is no one feature of dysplasia, it is a combination of findings. Young patients can have very atypical looking nevi that are completely benign. Requires experience; send to a Dermatopathologist if there is doubt.

In brief: Can be difficult

Identifying dysplastic nevi can be difficult.
There is a spectrum of changes in nevi, benign ->mild/moderate dysplasia->severe dysplasia->in-situ melanoma ->malignant (melanoma). There is no one feature of dysplasia, it is a combination of findings. Young patients can have very atypical looking nevi that are completely benign. Requires experience; send to a Dermatopathologist if there is doubt.
Dr. Marilda Chung
Dr. Marilda Chung
Thank
Dr. Ed Friedlander
Pathology

In brief: Pathologist opinion

Some nevi are borderline and one pathologist may call dysplasia while another gives a diagnosis of a related illness.
Genetic studies are still too pricey for routine use. Get several opinions, and the key is that if you've had a dysplastic nevus diagnosis, keep a VERY close eye on your skin, everywhere, for the rest of your life.

In brief: Pathologist opinion

Some nevi are borderline and one pathologist may call dysplasia while another gives a diagnosis of a related illness.
Genetic studies are still too pricey for routine use. Get several opinions, and the key is that if you've had a dysplastic nevus diagnosis, keep a VERY close eye on your skin, everywhere, for the rest of your life.
Dr. Ed Friedlander
Dr. Ed Friedlander
Thank
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