Related Questions

Colon cancer pt with 1 met in liver, 1 node, 1 sub pleural nodule. Chemo resistence. Tried Xeloda (capecitabine) and irinotecan both. Can anyting be done?

Try HT Concierge. Marilyn, given your situation, you need more advice that can be given in short answers like this. I would recommend a second opinion in England, In whatever regional center is best. In addition, consider health top concierge. Several excellent oncologists are available by searching. Hang in there! Read more...

What would be best chemo / treatment after irinotecan n Xeloda (capecitabine) failed for colon cancer with mets?

Difficult to answer. recommended chemotherapy regimens change regularly depending on the results of studies. Your oncologist should keep on top of those studies and will be able to recommend the next approved therapy or any experimental trials which may be available. I would talk further with your oncologist before making any plans. Good luck. Read more...

If Xeloda (capecitabine) and irinotecan alone not worked in colon cancer Pt, that mean no chemotherapy will work?

Others may help. If certain chemos do not give the proper response, one can take a fresh bx and send it for chemosensitivity and cahemoresistant studies. This will tell which wont work and which have the potentail to help either as single agents or combinations of drugs including use of immune drugs including Avastin (bevacizumab) and Erbitux. Read more...

What option is there if chemo fails for met colon cancer? Xeloda (capecitabine) n irinotecan failed

Oxaliplatin is good. Another good chemo drug is Oxaliplatin. This is often used in combination with 5-FU and Avastin (bevacizumab). If your tumor is KRAS wild type, then EGFR inhibitors(like Cetuximab and Panitumumab) also become relevant choices to use alone or in combination with other drugs. Read more...

10 liver mets and a node in metastic colon cancer. Xeloda (capecitabine) irinitecan failed. Can anything be done?

Yes. When colon Ca metastasizes to the liver it remains and progresses there with occasional node to porta. The first approach is to try chemoembolization after having an angiogram of the hepatic artery. This route can also be used for intrahepatic isotope administration. Systemically chemo plus avastin (bevacizumab) or Erbitux can be tried. New studies with Neo 102 are being offered in FDA trials . Read more...

Can any targeted therapies or other drugs help with metastic colon cancer when Xeloda (capecitabine) n irinotecan has failed?

Yes. Target agents that have activity either as single agent or as combination for recurrent or refractory metastatic colon cancer as a second line include: Avastin (bevacizumab) or Cetuximab/Panitumumab (if k-ras, n-ras, b-raf are wide type) or Regorafenib (inhibitor of angiogenic receptor) or aflibercept. FOLFOX may be effective too after irinotecan has failed. Clinical trials are aslo available. Read more...

If there is a liver met and 1 aortocaval node in a colon cancer pt, approx how many yrs is survival? Primary is removed n on irinotecan at present.

See liver specialist. Aortocaval LN involvement in colorectal cancer is unusual and should be confirmed by PET scan or biopsy before being labelled as a metastatic LN. If the liver metastasis can be resected, it should be resected. Adjuvant or neoadjuvant chemotherapy may improve long-term survival. Median survival for untreated Stage IV colorectal cancer is about 18 months. See a liver surgeon specialist. Read more...