Prilosec which ↓es. stomach acid production/24 hrs by ~1000 fold.Sounds like a lot, & is, but human stomach operating range is 1,000,000 fold, i.e. pH7 to pH1. The primary problem is gastric reflux related to brain control on esophageal muscle coordination & possibly pulling stomach up through diaphragm (called hiatal hernia). I have answered similar/related questions on Healthtap, suggest search & study.