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What is happening to the nervous system in Parkinson's disease?

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2 doctors agree

In brief: Degenerative

It is thought that cells containing dopamine are slowly and steadily deteriorating, and as a consequence, symptoms of shaking, poor gait, even memory loss become apparent.
It is also felt that the disorder presents pathologically in the brainstem first affecting the dorsal vagus and locus ceruleum early and later affects the basal ganglia. Deposition of Lewy Bodies becomes apparent within cells.

In brief: Degenerative

It is thought that cells containing dopamine are slowly and steadily deteriorating, and as a consequence, symptoms of shaking, poor gait, even memory loss become apparent.
It is also felt that the disorder presents pathologically in the brainstem first affecting the dorsal vagus and locus ceruleum early and later affects the basal ganglia. Deposition of Lewy Bodies becomes apparent within cells.
Dr. Bennett Machanic
Dr. Bennett Machanic
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1 comment
Dr. David Duncan m.d.
Cells communicate with each other with chemicals. Dopamine is one of those chemicals. The other brain cells can no longer hear what is being communicated. It is as if the brainstem is whispering and the other cells can not hear. The whispering spreads throughout other parts of the brain.
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Dr. Bennett Machanic
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