3 doctors weighed in:

What antidepressant medications selectively block neurotransmitters?

3 doctors weighed in
2 doctors agree

In brief: Most newer ones

Most of the newer antidepressant medications affect specific neurotransmitters.
Each does it slightly differently, accounting for the different response rates amongst them. The SSRI's primarily increase serotonin, the SNRI's both serotonin and norepinephrine, and buproprion mostly norepinephrine alone, and Brintellix affects many of them in different ways and in different places in the brain.

In brief: Most newer ones

Most of the newer antidepressant medications affect specific neurotransmitters.
Each does it slightly differently, accounting for the different response rates amongst them. The SSRI's primarily increase serotonin, the SNRI's both serotonin and norepinephrine, and buproprion mostly norepinephrine alone, and Brintellix affects many of them in different ways and in different places in the brain.
Dr. Alan Koenigsberg
Dr. Alan Koenigsberg
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