1 doctor weighed in:

Can any targeted therapies or other drugs help with metastic colon cancer when Xeloda (capecitabine) n irinotecan has failed ?

1 doctor weighed in
Dr. Le Wang
Internal Medicine

In brief: Yes

Target agents that have activity either as single agent or as combination for recurrent or refractory metastatic colon cancer as a second line include: Avastin (bevacizumab) or Cetuximab/Panitumumab (if k-ras, n-ras, b-raf are wide type) or Regorafenib (inhibitor of angiogenic receptor) or aflibercept.
FOLFOX may be effective too after irinotecan has failed. Clinical trials are aslo available.

In brief: Yes

Target agents that have activity either as single agent or as combination for recurrent or refractory metastatic colon cancer as a second line include: Avastin (bevacizumab) or Cetuximab/Panitumumab (if k-ras, n-ras, b-raf are wide type) or Regorafenib (inhibitor of angiogenic receptor) or aflibercept.
FOLFOX may be effective too after irinotecan has failed. Clinical trials are aslo available.
Dr. Le Wang
Dr. Le Wang
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