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Does the benefit of tysabri (natalizumab) outweigh the risk of PML ?

1 doctor weighed in
Dr. Julie Abbott
Preventive Medicine

In brief: Individualized

Tysabri/natalizumab is an immunosuppressant used in the treatment of relapsing forms of MS.
PML (progressive multifocal leukoencephaolopathy),the result of JC virus infection, is a disastrous side effect.The decision to use this drug has to be very cautiously assessed by the MS patient & his doctor & administered through a restricted program. Risk/benefit analysis is complicated & challenging.

In brief: Individualized

Tysabri/natalizumab is an immunosuppressant used in the treatment of relapsing forms of MS.
PML (progressive multifocal leukoencephaolopathy),the result of JC virus infection, is a disastrous side effect.The decision to use this drug has to be very cautiously assessed by the MS patient & his doctor & administered through a restricted program. Risk/benefit analysis is complicated & challenging.
Dr. Julie Abbott
Dr. Julie Abbott
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