Is on and off cramping for a few days mid cycle a sign of pregnancy?

Probably not. Hi Eugene, Cramping can be caused by many factors. Too many to name just now. But consider that ovulation occurs mid-cycle. There are so many hormonal changes at this time. The uterus is a hormone sensitive organ and responds in 1 of 2 ways. It either cramps &/or bleeds. I would say that mid cycle cramping is expected and normal, therefore do not worry.