Which chemo therapy is most effective for KRAS mutant metastic colon cancer?

Same drugs as other. Same chemotherapy drugs are used for treating both types of colon cancer. The only difference is lack of benefit from EGFR inhibitors(Cetuximab and Panitumumab). Avastin (bevacizumab) also works in both types. I trust that you know there are 3 chemo drugs that are widely used(5FU or Capecitabine, Irinotecan and Oxaliplatin)

Related Questions

3 cycles of chemotherapy so far for metastic colon cancer shows therapy working, if 2 cycles are missed due to ill health, will cancer start growing agsin?

No way to know. Metastatic cancer is very unpredictable. Best to follow it and your other health problems with your oncologist. Good luck. Read more...
Cancer grow again. Instead of thinking will the cancer grow again with not enough chemo, ask the question, were the cancer cells killed enough? With not enough cycles of chemo, chances are strong they weren't. Better see your Hemo-Onc doctor to get your chemo tx back on track. Read more...
No. If 3 cycles of chemo given and well tolerated, evaluation might show stability or regression if drugs working. If missing 2 cycles, this will not allow further regression while off medication, but if resumed a further response may be defined. Most combo drugs for colon cancer may show a termporary response but not cure. The newer combinations with Immunochemotherapy more effective. Read more...

How effective r chemotherapy uft pills in metastic colon cancer?

Some response. meds like Xeloda have some tempoary benefit suppressing DNA function as an oral 5FU (fluorouracil). Long term responses are not seen requiring combination therapy to give an optimjum response. Eventually if cancer does show a good response, malignant stem cells will repopulate the site of the original metastasis. Read more...

Ihow effective are uft chemotherapy pills for metastic colon cancer?

Modestly effective. Fluoropyrimidines (5-FU, Capecitabine and UFT) as a class have modest activity and one of these 3 needs to be combined with Oxaliplatin and or Irinotecan to achieve best results ,as combination chemo is far superior in efficacy than any single chemo drug. Read more...

What is prognosis With chemotherapy for metastic colon Cancer?

So many variables. Too many variables to give you a pertinent answer. Consult your oncologist to help you with clinical decisions. Read more...

What can prognosis b like for metastic colon cancer that chemotherapy oxyplatin and raltitrexed?

Colon mets. Not having your chart and you in front of me makes it very hard to give you an accurate idea on prognosis. When chemo is started, that means your CA cells have gone beyond the boundaries which would have made txing it simple. The simpler the tx, the better the prgns. The harder the tx, the worse the prgns. On a positive note, f/u with your docs, stay faithful, and you might get a pleasant surprise. Read more...

Can Radiotherapy be used for metastic colon cancer if chemotherapy is resistant?

Selected instances. Metastatic colon cancer when in multiple areas and non resectable reequires chemotherapy. Radiation can not be used systemically and is delivered to a single site. If mass is large, in preparation for resection, radiation has been employed. New monoclonals being developed thatt have alpha emmitters and can be delivered to colon Ca as a form of internal radiation. Read more...
Not often. Radiotherapy can be useful in certain select cases where the Cancer is localized to one or two spots only. This means 1 patient in 5 may be suitable candidate. But you need to seek consultation with a radiation oncologist before you can get a clear cut answer for your circumstances. Read more...

What can approx prognosis b for metastic colon cancer with chemotherapy?

What kind of mets. it depends what kind of metastases we are talking about. if the spread to the lymph nodes, surgery and chemotherapy, and possible radiation therapy could be very helpful. if the spread to the liver the prognosis is less optimistic, unless the metastases are able to be resected. other metastases are less promising in spite of chemotherapy and radiation therapy .like bone and brain. Read more...
Temporary relief. The best chemo can offer metastatic colon cancer is a temporary relief of symptoms and possibly some tumor shrinkage There are no known cures from chemo due to the presence of malignant stem cells that have repairative mechanisms for damaged DNA. If the lesion is in the liver, one can attempt primary resection or microwave ablation.. Shrinkage here can leade to resection and possible cure. Read more...

If chemotherapy fails for metastic colon cancer what option is there?

What do you mean? my first question is what do you mean chemotherapy fail. what kind of symptoms the patient has to indicate failure. and to answer your question, if surgery is no longer an option to control the metastases. then it is wait and see. Read more...

Can 1 drop in cea at round 2 of chemotherapy suggest anything. Drop from 65 to 55.? Metastic colon cancer pt

Cea levels . Oncologist use CEA markers to assess the success in cancer chemotherapy regimens. A drop in CEA after chemotherapy is a positive sign. This means the chemotherapy is working. Have a great day! . Read more...