20 doctors weighed in:

9 antidepressants didn't work, still suffer from major depression, what are other treatment options for the depression?

20 doctors weighed in
Dr. Matt Malkin
Anesthesiology
7 doctors agree

In brief: Other meds

Other classes of meds may work.
Diagnosis needs to be reconfirmed. May benefit from electroconvulsive therapy as last resort. Ect is done under a short general anesthetic. Your psychiatrist will advise.

In brief: Other meds

Other classes of meds may work.
Diagnosis needs to be reconfirmed. May benefit from electroconvulsive therapy as last resort. Ect is done under a short general anesthetic. Your psychiatrist will advise.
Dr. Matt Malkin
Dr. Matt Malkin
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7 doctors agree

In brief: Re-eval

When this kind of things happens then we need to start thinking about a misdiagnosis.
You should get re-evaluated to clarify your diagnosis of depression. If this is indeed mdd then there are diferent options to deal with treatment resistant depression like adjunctive therapy with a antidepressant with a mood stabilizer, combination of antidepressant or electro convulsive therapy.

In brief: Re-eval

When this kind of things happens then we need to start thinking about a misdiagnosis.
You should get re-evaluated to clarify your diagnosis of depression. If this is indeed mdd then there are diferent options to deal with treatment resistant depression like adjunctive therapy with a antidepressant with a mood stabilizer, combination of antidepressant or electro convulsive therapy.
Dr. Antonio Garcia Merino
Dr. Antonio Garcia Merino
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1 comment
Dr. Kimberly Erway
Consider ECT
Dr. Paul Schwartz
Psychiatry
5 doctors agree

In brief: Still have options

Assuming you've taken antidepressants in all classes (ssris: e.
g. Prozac, zoloft; snris: cymbalta, (duloxetine) effexor; ne/da reuptake inhibitor wellbutrin; mixed action: remeron; tca's: e.g. Imipramine, desipramine), then either you should try an maoi (parnate or nardil), which work well for treatment refractory depression, or you may have bipolar depression, which requires different types of medications.

In brief: Still have options

Assuming you've taken antidepressants in all classes (ssris: e.
g. Prozac, zoloft; snris: cymbalta, (duloxetine) effexor; ne/da reuptake inhibitor wellbutrin; mixed action: remeron; tca's: e.g. Imipramine, desipramine), then either you should try an maoi (parnate or nardil), which work well for treatment refractory depression, or you may have bipolar depression, which requires different types of medications.
Dr. Paul Schwartz
Dr. Paul Schwartz
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Dr. Andrew Ho
Psychiatry
2 doctors agree

In brief: Try psychotherapy

It used to be psychotherapy first, then, if still not better, antidepressants or ECT are used.
Now that drugs are more economical than psychotherapy, it is typical to start with drugs. Failing so many drugs makes me think psychotherpy may be necessary, or there is something else going on. For example, alcohol and drug abuse will cause symptoms that look exactly like depression.

In brief: Try psychotherapy

It used to be psychotherapy first, then, if still not better, antidepressants or ECT are used.
Now that drugs are more economical than psychotherapy, it is typical to start with drugs. Failing so many drugs makes me think psychotherpy may be necessary, or there is something else going on. For example, alcohol and drug abuse will cause symptoms that look exactly like depression.
Dr. Andrew Ho
Dr. Andrew Ho
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Dr. Pavel Conovalciuc
Family Medicine
1 doctor agrees

In brief: Misdignosed

Well.....There is a good chance you have a different diagnosis than major depression.
You may have features of it, but the real one is different. Also, when you say they didn't work, what do you mean? Did you try them long enough? Did any of them work initially but quit working later? Are there any unresolved life issues that you are trying to mitigate by taking antidepressants? Let us know!

In brief: Misdignosed

Well.....There is a good chance you have a different diagnosis than major depression.
You may have features of it, but the real one is different. Also, when you say they didn't work, what do you mean? Did you try them long enough? Did any of them work initially but quit working later? Are there any unresolved life issues that you are trying to mitigate by taking antidepressants? Let us know!
Dr. Pavel Conovalciuc
Dr. Pavel Conovalciuc
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Dr. Evan Hirsch
Integrative Medicine

In brief: Find the cause

Causes include food allergies, nutrient, fatty acid, Amino Acid deficiencies and dehydration.
Find the cause, find the cure.

In brief: Find the cause

Causes include food allergies, nutrient, fatty acid, Amino Acid deficiencies and dehydration.
Find the cause, find the cure.
Dr. Evan Hirsch
Dr. Evan Hirsch
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Dr. Alan Ali
Psychiatry

In brief: Treatment Resistant

Treatment-resistant depression is treated with other psychotropic medications such as lithium, Abilify (aripiprazole) or seroquel.
Consult your md for such.

In brief: Treatment Resistant

Treatment-resistant depression is treated with other psychotropic medications such as lithium, Abilify (aripiprazole) or seroquel.
Consult your md for such.
Dr. Alan Ali
Dr. Alan Ali
Thank
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