How can I get rid of syphilis?

Antibiotics. Single large dose of penicillin or Azithromycin usually cures syphilis. Some strains of syphilis bacteria are resistant to a number of antibiotics so follow up is required. Syphilis is usually cured when the intial syphilitic sore (chancre) has healed.
Syphilis. Syphilis is a severe disease. You must obtain specialty care to completely diagnosis and then appropriately treat you for this disease. You should call your doctor asap. Also remember that you can infect others until the syphilis cured. Call your doctor today.