Yes...maybe . Here are two extremes. A monogamous heterosexual couple has one partner who finds out he has hcv. If the other partner is negative the cdc does not recommend condom use. On the other hand, we have an epidemic of hcv in men who have unprotected anal sex with other men. Condom use is strongly recommended in this case. New partners should use condoms for hcv, hiv, hep b, syphilis, gc, chlamydia, etc.