Pigmented lesion. In face. Recent increase size. Irregular border....Biopsy reveals malignant cells infiltration. ..Whats diagnosis plz?

Can be melanoma. This sounds like melanoma. You're lucky to have found this out on biopsy, as removal of this can be 100% curative. It's really smart to talk this over with your doctor, as well as the treatment options so you know what you're dealing with.