End stage kidney disease (pkd). Recurrent infections since apr, 12. Been on levoflox 500 since then. Noticed redness of skin in the leg. Is the drug safe?

PKD and levofloxacin. Levofloxacin is a good medication, though can have tendon side effects. Cipro (ciprofloxacin) and Levo are especially good for PKD associated infections. Redness of leg skin may reflect some edema -- is there evidence of rash on trunk or arms?
Safe for what? Levofloxacin is safe enough to have been approved by fda but all drugs have (potential) side effects. It carries 2 black box warnings: one re tendinitis & tendon rupture; other re myasthenia gravis. You didn't mention how often you're taking this antibiotic (or for what reason) nor did you mention your crcl but frequency is typically adjusted according to crcl eg every 48hr if crcl 10-19.