What is the fastest way to get rid of a normal headache?

NSAIDS. Non steroidal anti-inflammatory drugs (nsaids) like ibuprophen, Aspirin or naproxin, will soothe most headaches; Acetaminophen (tylenol (acetaminophen)) will work as well. Be sure to read the directions on the bottle carefully before you take them. Nsaids and tylenol (acetaminophen) can lead to rebound headaches if abused; if your headaches persist, make sure to see your doctor.
Headache. Get rid of the cause. There is textbook on headache alone. The causes are multiple and the treatment may be varied. Tylenol (acetaminophen) and nsaid's may be a good first line to treatment.