If Depo-Provera estradiol is use to relieve menopause symptoms, will it also cause withdrawal like severe body aches and pains/flu like symptoms if stop using?

Postpones, not cure. If you take estrogen to alleviate menopausal symptoms, you are postponing them until such time as you stop the estrogen replacement. Then they will occur just like they would have at your time of menopause had you not elected to begin the estrogen replacement.