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Where does the penicillin acctask the bacteria ?

2 doctors weighed in
Dr. Booth Wainscoat
Internal Medicine - Infectious Disease
1 doctor agrees

In brief: PBP (its complicated

Bacteria have a cell wall for protection.
The building blocks of this wall are peptidoglycan (pg). Pg is arranged in 2 ways to make 2 types of bacteria: gram (+) or gram (-). Penicillin (pcn) only works in gram (+) bacteria. Pg must be cross-linked to protect the bacteria. Pcn attaches to pbp's (penicillin binding proteins) which prevents pg cross-linking. Some bacteria have pbp's resistant to pcn.

In brief: PBP (its complicated

Bacteria have a cell wall for protection.
The building blocks of this wall are peptidoglycan (pg). Pg is arranged in 2 ways to make 2 types of bacteria: gram (+) or gram (-). Penicillin (pcn) only works in gram (+) bacteria. Pg must be cross-linked to protect the bacteria. Pcn attaches to pbp's (penicillin binding proteins) which prevents pg cross-linking. Some bacteria have pbp's resistant to pcn.
Dr. Booth Wainscoat
Dr. Booth Wainscoat
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