10 doctors weighed in:

Have the experts figured out what causes alzhiemers in younger people ?

10 doctors weighed in
Dr. Theresa Redling
Internal Medicine - Geriatrics
3 doctors agree

In brief: Often genetic

Familial ad(fad) is often a result of presenilin genes that are passed on via our genetics.
It is uncommon, but you will see large amount of family members affected by ad often before age 50. A times, there maybe a mutation responsible for the ad, that will not be passed on in the genes to other family members. T.

In brief: Often genetic

Familial ad(fad) is often a result of presenilin genes that are passed on via our genetics.
It is uncommon, but you will see large amount of family members affected by ad often before age 50. A times, there maybe a mutation responsible for the ad, that will not be passed on in the genes to other family members. T.
Dr. Theresa Redling
Dr. Theresa Redling
Thank
2 doctors agree

In brief: Some causes

We know about 50% of the genes for young onset ad: presenilin 1 accounts for about 45%.
Presenilin 2 and app mutations account for 1-2%. The apo-e gene is a risk factor for late onset disease (usually after age 60). The alzheimer's association has more information and a video about genetic causes: http://www.Alz.Org/alzheimers_disease_early_onset.Asp.

In brief: Some causes

We know about 50% of the genes for young onset ad: presenilin 1 accounts for about 45%.
Presenilin 2 and app mutations account for 1-2%. The apo-e gene is a risk factor for late onset disease (usually after age 60). The alzheimer's association has more information and a video about genetic causes: http://www.Alz.Org/alzheimers_disease_early_onset.Asp.
Dr. Darren Gitelman
Dr. Darren Gitelman
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Dr. Alvin Lin
Internal Medicine - Geriatrics
2 doctors agree

In brief: Yes & No

In some very rare situations, there are families where just about everyone develops azlheimer's disease at a very young age.
The most famous is in medellin, colombia. There is also an autosomal dominant group which was published in nejm http://ow.Ly/cbgta. We can test for apoe4 but that doesn't necessarily imply younger age at diagnosis nor is it very predictive.

In brief: Yes & No

In some very rare situations, there are families where just about everyone develops azlheimer's disease at a very young age.
The most famous is in medellin, colombia. There is also an autosomal dominant group which was published in nejm http://ow.Ly/cbgta. We can test for apoe4 but that doesn't necessarily imply younger age at diagnosis nor is it very predictive.
Dr. Alvin Lin
Dr. Alvin Lin
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Dr. Pedro Hernandez
Internal Medicine - Geriatrics
1 doctor agrees

In brief: No

No.

In brief: No

No.
Dr. Pedro Hernandez
Dr. Pedro Hernandez
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1 comment
Dr. Ramin Rafie
Generally no, genetics is believed to have some contribution in some types of dementia.
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