Does having sickle cells affect a woman having kids?

Possibly. Sickle cell disease (scd) probably has little effect on fertility. However, sickle crisis can be more frequent in pregnancy and the impaired oxygenation due to scd can affect the growth and development of the fetus. There is also an increased risk for preterm labor and premature delivery. Because of the increased risks, a pregnancy complicated by scd should be followed by a perinatologist.