Thick green yellow mucus running from nose after 1 week of cold with large clear colored nasal discharge?

Flora shifting. If no fevers or significant pain--let it run! in fact, take Mucinex (guaifenesin) to keep things thin and flowing. Your body is likely re-balancing the flora in its sinuses, and this should stop about double the time you were sick. If fevers/pain, then see dr / urgent care.