5 doctors weighed in:
Can a person who takes Imitrex (sumatriptan) for migraines build a tolerance to the drug?  having to eventually increase dose or change medications?
5 doctors weighed in

Dr. Edward Neilsen
Family Medicine
3 doctors agree
In brief: Is it the right med?
I have seen many, many people who do not respond to typical migraine medications (imitrex, relpax, (eletriptan) maxalt, etc) because they don't have true migraines.
Often time any bad headache is diagnosed as a migraine. There are many other types of headaches that can be just as bad (tension, cluster, rebound, etc) that do not respond to those treatments. Confirm that your diagnosis is correct first!

In brief: Is it the right med?
I have seen many, many people who do not respond to typical migraine medications (imitrex, relpax, (eletriptan) maxalt, etc) because they don't have true migraines.
Often time any bad headache is diagnosed as a migraine. There are many other types of headaches that can be just as bad (tension, cluster, rebound, etc) that do not respond to those treatments. Confirm that your diagnosis is correct first!
Dr. Edward Neilsen
Dr. Edward Neilsen
Thank
2 comments
Dr. Edward Neilsen
Not usually. If it works on day #1, it will usually work for a long time.
Dr. Kenneth Choquette
Most HA are cervicogenic, coming from the neck and not responsive to migraine meds. Look there.
Dr. Kenneth Choquette
Pain Management
1 doctor agrees
In brief: Maybe
But a more accurate explanation is that you may be treating the wrong condition with the wrong med.
Since many people have mixed headache patterns, and since most bad headaches come out of the neck, these pain patterns will not respond to triptans. Many people have secondary migraines where the triptan will help, but if more of your pain is from other comditions, then you will need different tx.

In brief: Maybe
But a more accurate explanation is that you may be treating the wrong condition with the wrong med.
Since many people have mixed headache patterns, and since most bad headaches come out of the neck, these pain patterns will not respond to triptans. Many people have secondary migraines where the triptan will help, but if more of your pain is from other comditions, then you will need different tx.
Dr. Kenneth Choquette
Dr. Kenneth Choquette
Thank
Get help from a real doctor now
Dr. Vikram Patel
Board Certified,
33 years in practice
926K people helped
Continue
107,000 doctors available
Read more answers from doctors