What could snorting norco (hydrocodone and acetaminophen) up your nose do to your face?

Irritate it. Snorting anything up your nose can irritate the mucus membranes in your nose or throat and can potentially cause swelling or bleeding. It is certainly not the intended use for Norco (hydrocodone and acetaminophen) or any other oral medication and is not recommended. Norco (hydrocodone and acetaminophen) is a combination of Acetaminophen (tylenol) and hydrocodone, a powerful opioid narcotic. Too much Norco (hydrocodone and acetaminophen) can cause respiratory arrest and even death.