What is the best way to manage arthritis?

Stay active. Arthritis can be thought of as rust in the joint, and staying active is the best way to keep the joints moving freely. Tylenol (acetaminophen) can also be helpful, and sometimes injections (depending on the joint) can provide a great deal of relief.
Which type? There are a lot of different types of arthritis. Depending on the type you have will direct the treatment. Different medications will need to be used for different types of arthritis. Most arthritis will require correct exercise, correct physical therapy directed again depending on the type of arthritis.