6 doctors weighed in:
Can you explain the mechanism fever ?
6 doctors weighed in

Dr. Booth Wainscoat
Internal Medicine - Infectious Disease
5 doctors agree
In brief: Yes I can :)
Fever results from a chemical cascade in response to a pyrogen.
Infection causes the release of pyrogens which in turn cause the body to produce a chemical called prostaglandin e2 (pge2). Pge2 then stimulates a special part of our brain's hypothalamous called the pre-optic area (poa). The poa then integrates this information and sends a signal to our autonomic nervous system to create heat.

In brief: Yes I can :)
Fever results from a chemical cascade in response to a pyrogen.
Infection causes the release of pyrogens which in turn cause the body to produce a chemical called prostaglandin e2 (pge2). Pge2 then stimulates a special part of our brain's hypothalamous called the pre-optic area (poa). The poa then integrates this information and sends a signal to our autonomic nervous system to create heat.
Dr. Booth Wainscoat
Dr. Booth Wainscoat
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