Can I drink and/or smoke marijuana while on effexor (venlafaxine)? I switched from 200mg Zoloft to 75mg Effexor (venlafaxine) just yesterday for anxiety cuz Zoloft wasnt working

No. It is never recommended to drink or take drugs especially with your medications.
Not wise to combine. Effexor (venlafaxine) affects levels of neurotransmitters in our brain & caution should be taken when combining it with any other chemicals that affect our minds. I wasn't able to find specific info on marijuana & Effexor (venlafaxine) but found this info on how it interacts with Marinol (synthetic thc) & alcohol:http://www.Drugs.Com/drug-interactions/effexor-with-marinol-2296-1524-943-511.Html ps it's wise to ask your doc.