6 doctors weighed in:

How is Neurontin (gabapentin) processed in the body and what are the side effects?

6 doctors weighed in
Dr. Einar Ottestad
Pain Management
4 doctors agree

In brief: Min

Gabapentin is extremely safe.
It is not metabolized by the lover and is excreted unchanged by the kidney. It is also actively absorbed in the small intestine so if you drank a gallon of it, most would not even be absorbed, just pooped out. No liver/kidney/heart/stomach toxicity. Doesnt interact with other meds. Se are mainly sedation unless titrated slowly, weight gain, and swelling.

In brief: Min

Gabapentin is extremely safe.
It is not metabolized by the lover and is excreted unchanged by the kidney. It is also actively absorbed in the small intestine so if you drank a gallon of it, most would not even be absorbed, just pooped out. No liver/kidney/heart/stomach toxicity. Doesnt interact with other meds. Se are mainly sedation unless titrated slowly, weight gain, and swelling.
Dr. Einar Ottestad
Dr. Einar Ottestad
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Dr. Paul Reynolds
Pain Management
1 doctor agrees

In brief: Kidney

Sleepiness and confusion are common complaints.
Some complain of weight gain. There are reports of depression. Most find it helpful. Keeping the dose low tends to lessen side effects.

In brief: Kidney

Sleepiness and confusion are common complaints.
Some complain of weight gain. There are reports of depression. Most find it helpful. Keeping the dose low tends to lessen side effects.
Dr. Paul Reynolds
Dr. Paul Reynolds
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Dr. David Rosenfeld
Pain Management

In brief: Pretty simple

Neurontin (gabapentin) is not metabolized.
It is eliminated by the kidneys. Because the elimination of Neurontin (gabapentin) is entirely renal, patients with renal insufficiency usually need lower dosages and less frequent dosing. Side effects of Neurontin (gabapentin) are generally mild to moderate and transient. The most commonly reported dose-related side effects are: drowsiness dizziness fatigue.

In brief: Pretty simple

Neurontin (gabapentin) is not metabolized.
It is eliminated by the kidneys. Because the elimination of Neurontin (gabapentin) is entirely renal, patients with renal insufficiency usually need lower dosages and less frequent dosing. Side effects of Neurontin (gabapentin) are generally mild to moderate and transient. The most commonly reported dose-related side effects are: drowsiness dizziness fatigue.
Dr. David Rosenfeld
Dr. David Rosenfeld
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