13 doctors weighed in:

How does metformin help pcos symptoms?

13 doctors weighed in
Dr. Cayce Jehaimi
Pediatrics - Endocrinology
5 doctors agree

In brief: Many functions

Metformin continues to impress us as physicians with its ability to restore many endocrine functions gone awry.
Some of its mechanisms we still dont know but for the most part and particularly in women with pcos and Insulin resistance component, metformin helps in decreasing Insulin resistance which in turn will lower total Insulin production and reduce ovarian production of testosterone.

In brief: Many functions

Metformin continues to impress us as physicians with its ability to restore many endocrine functions gone awry.
Some of its mechanisms we still dont know but for the most part and particularly in women with pcos and Insulin resistance component, metformin helps in decreasing Insulin resistance which in turn will lower total Insulin production and reduce ovarian production of testosterone.
Dr. Cayce Jehaimi
Dr. Cayce Jehaimi
Thank
Dr. Vered Lewy-Weiss
Pediatrics - Endocrinology
2 doctors agree

In brief: Insulin sensitivity

Resistance to Insulin (ir) causes the pancreas to make lots of insulin.
This increase interferes in the normal menstrual cycle and also warps lipids. Additionally, the overworked pancreas is at risk for wearing out, leaving one with a high risk for developing diabetes. Metformin decreases ir which helps the body need less insulin.

In brief: Insulin sensitivity

Resistance to Insulin (ir) causes the pancreas to make lots of insulin.
This increase interferes in the normal menstrual cycle and also warps lipids. Additionally, the overworked pancreas is at risk for wearing out, leaving one with a high risk for developing diabetes. Metformin decreases ir which helps the body need less insulin.
Dr. Vered Lewy-Weiss
Dr. Vered Lewy-Weiss
Thank
Dr. Mark Perloe
Fertility Medicine
2 doctors agree

In brief: PCOS and sugar

A majority of women with pcos have normal sugar levels and normal fasting insulin.
It is usually only after a sugar load is the marked Insulin resistance evident. Too often physicians suggest a women won't benefit from metformin because glucose is normal. That is not true. Best results happen when metformin is combined with exercise and low glycemic diet. www.ivf.com/pcostreat.html.

In brief: PCOS and sugar

A majority of women with pcos have normal sugar levels and normal fasting insulin.
It is usually only after a sugar load is the marked Insulin resistance evident. Too often physicians suggest a women won't benefit from metformin because glucose is normal. That is not true. Best results happen when metformin is combined with exercise and low glycemic diet. www.ivf.com/pcostreat.html.
Dr. Mark Perloe
Dr. Mark Perloe
Thank
Dr. Joshua Klein
Fertility Medicine
1 doctor agrees

In brief: Glucose/insulin

Part of the problems caused by pcos can be elevated levels of glucose (sugar) and Insulin (the hormone that regulates glucose), both generally in the body and locally in the ovary.
Metformin is a diabetes medication that helps decrease Insulin and glucose levels, thereby improving your ability to ovulate (and possibly the quality of the eggs too).

In brief: Glucose/insulin

Part of the problems caused by pcos can be elevated levels of glucose (sugar) and Insulin (the hormone that regulates glucose), both generally in the body and locally in the ovary.
Metformin is a diabetes medication that helps decrease Insulin and glucose levels, thereby improving your ability to ovulate (and possibly the quality of the eggs too).
Dr. Joshua Klein
Dr. Joshua Klein
Thank
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