Related Questions

How safe is hormone replacement therapy if family history breast cancer?

Short term safety. There is no apparent increased risk for short term use of hormone therapy, with or without a family history. For longer term use (greater than 4 years) it is not clear exactly how the different estrogen and Progesterone formulations and combinations affect risk. Read more...
Varies. If a first order relative (mother, sister, daughter) has bc i would take ert only briefly and then only for severe symptoms. Remember that we try to prevent breast cancer by prescribing tamoxifen - which blocks estrogen. Adding ert definitely increases risk, somewhat, so you have to balance risks/benefits. Some women are miserable without it - and a short course may be appropriate for them. Read more...

Does hormone replacement therapy for menopausal symptoms cause breast cancer?

It can. The cause of breast cancer is so complex and poorly understood that it's better to talk about "associations" rather than "causes". Studies have shown that women who have used hormone replacement have a slightly higher incidence of breast cancer as compared to women that have not. In general, if you can avoid it, it's better to, especially if you have other risk factors for breast cancer. Read more...
In short, no. There are three human esrogens: Estradiol (from the ovary), estriol (from the placenta in pregnancy) and estrone (from peripheral fat conversion). Estrone is probably the culprit since women with excess peripheral body fat have increase rates of estrogen related cancers (breast, uterus, ovary, colon). Many oral estrogen hormones on the market are converted to estrone in the liver. Read more...
Increases risk. Hormone replacement therapy (hrt) has been shown to increase one's risk for breast cancer if taken for longer than 5 years. The current recommendation is to take low doses for a limited amount of time and then stop. There are some other non hormonal medications that can be used to help manage menopausal symptoms. Read more...
Depends. Virtually all of the studies showing that hrt increases breast cancer have been done on premarin (conjugated estrogens). Premarin (conjugated estrogens) is converted to estrone in the liver when taken orally. Overweight women convert adrenal hormones into estrone in peripheral body fat & have increased rates of estrogen dependent cancers (breast, colon, uterine). I suspect the culprit is estrone, not estradiol/estriol, the other human estrogens. Read more...

Hello doctor, I am on a hormone replacement therapy for menopause. Could this cause some pain in breasts?

Yes. Occasional mild breast tenderness on post-menopausal hormone therapy is not uncommon.It may however indicate that your dosing is too high. There is variation in the metabolism of estrogen in different women. Alcohol consumption may slow the clearance of estrogen. Breast pain in general needs evaluation. You should schedule an appointment with the doctor that prescribed your estrogen. Read more...

Does hormone replacement therapy increase your chances for breast cancer expotentionally?

Not exponentially. Data from the whi (women's health initiative) study show that estrogen alone does not significantly increase the risk of breast cancer, especially if started within 5 years of menopause. However, estrogen + Progesterone (needed when women still have a uterus to prevent uterine cancer) increases the risk of breast cancer to about 2x the baseline risk. Progesterone appears to be the "bad guy". Read more...
No. But long-term exposure is probably assocaited with a greater risk of breast cancer. But the actual risk is hard to prove and is certainly not exponential. Still, best not to take ert for more than 5 years unless you are very sympomatic from menopausal symptoms. Read more...
Absolutely Not. The whi as now reviewed was a very poor study overall and likely answers few clinical questions. I agree with the former answer that the progestin component was implicated but would not implicate Progesterone specifically. It was provera, (medroxyprogesterone) a synthetic Progesterone used in the study. The study population does not represent the typical patient we see. You need a consultation with hormone dr. Read more...

Hormone replacement therapy. Estrogen alone increases risk of uterine cancer. Adding progesterone increases risk of breast cancer, but reduces risk of uterine cancer. What's the right balance?

Individual. Yes, estrogen alone does increase the risk of uterine cancer over time. And yes the whi showed that the combination of a certain synthetic estrogen and a certain synthetic progestin increased the risk of breast cancer. But most specialists do not use those older types of synthetic hormones and with newer medications the risks are lower and different. So a balance can be achieved. Read more...

Is 20 yr old a good age to start hormone replacement therapy to become a female?

A Team Decision. Any one considering a gender re-assignment should be comprehensively evaluated by a team consisting of a psychiatrist, psychologist and endocrinologist as well as a sexual re-assignment plastic surgeon. There are too many factors involved in making the decision to pursue re-assignment, rather than say any particular age is okay. Read more...