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Is malaria and sickle cell anemia related?

5 doctors weighed in
Dr. Heidi Fowler
Psychiatry
2 doctors agree

In brief: Sickle cell Trait

can offer some protective value regarding severity of malarial disease.
In a person who has sickle-cell trait – the red blood cells are destroyed prematurely before the Plamodium can reproduce. According to one study “Sickle cell trait provides 60% protection against overall mortality. Most of this protection occurs between 2-16 months of life, before the onset of clinical immunity..."

In brief: Sickle cell Trait

can offer some protective value regarding severity of malarial disease.
In a person who has sickle-cell trait – the red blood cells are destroyed prematurely before the Plamodium can reproduce. According to one study “Sickle cell trait provides 60% protection against overall mortality. Most of this protection occurs between 2-16 months of life, before the onset of clinical immunity..."
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1 comment
Dr. Heidi Fowler
intense transmission of malaria.” See: http://www.cdc.gov/malaria/about/biology/sickle_cell.html ** This is not the case for a person with sickle-cell disease.
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