2 doctors weighed in:

Can barretts metaplasia (no dysplasia) progress directly to adenocarcinoma of esophegus within 4 months of egd scopy?

2 doctors weighed in
Dr. Todd Abbott
Pathology
1 doctor agrees

In brief: Unlikely

Does your question signal that it did happen? Even if biopsies are negative for dysplasia, biopsies are just that, biopsies of a larger lesion.
Biopsies always have the chance of having sampling error...Meaning the most severe part of the lesion was not sampled. The risk of sampling error would go up with a larger lesion than was minimally, and not systematically, biopsied.

In brief: Unlikely

Does your question signal that it did happen? Even if biopsies are negative for dysplasia, biopsies are just that, biopsies of a larger lesion.
Biopsies always have the chance of having sampling error...Meaning the most severe part of the lesion was not sampled. The risk of sampling error would go up with a larger lesion than was minimally, and not systematically, biopsied.
Dr. Todd Abbott
Dr. Todd Abbott
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